School of Biological Sciences, Monash University, Victoria, Australia
Extending healthy lifespan by moderate dietary restriction is one of the few interventions accessible to the general public. Several recent studies have pointed to the importance of dietary macronutrient balance as key for its beneficial effects. Using Drosophila melanogaster, we have been concentrating on the role of dietary protein. In particular, we have found that altering the amino acid balance to match the genome of the consumer gives a definition of high quality protein that promotes early life vigour at protein concentrations low enough to avoid cost to lifespan. I will discuss the roles of dietary amino acid balance in dictating health and lifespan outcomes.